Axiostat Trauma

Technology

Protonated Bioadhesive Technology (PBT®)

Axio Biosolutions leverages on its proprietary Protonated Bioadhesive technology (PBT®) to develop 100% chitosan-based Axiostat Haemostatic dressing for rapid control of moderate to severe bleeding in emergency and trauma scenarios.
Protonated Bioadhesive Technology (PBT®) includes 4 major steps including charge-based interaction with blood components, platelet activation via Toll-like receptors (TLR) Clotting cascade activation and robust fibrin plug formation at the bleeding site

How Axiostat Effectively Stops Bleeding in Emergencies & Trauma

Resting Platelets
Activated Platelets

Resting Platelets

Activated Platelets

Resting Platelets
Activated Platelets
Resting Platelets
Activated Platelets

Prothrombin

Factor X Activation

Thrombin

Thrombin

Fibrinogen

Resting Platelets
Activated Platelets

Prothrombin

Factor X Activation

Thrombin

Thrombin

Fibrinogen

Resting Platelets
Activated Platelets

Prothrombin

Factor X Activation

Thrombin

Thrombin

Fibrinogen

Resting Platelets
Activated Platelets

Prothrombin

Factor X Activation

Thrombin

Fibrin Clot

Fibrinogen

How Axiostat Effectively Stops Bleeding in Emergencies & Trauma

1.

Charged–based adhesion between  blood  components and Axiostat
Resting Platelets
Activated Platelets

Prothrombin

Factor X Activation

Thrombin

Fibrin Clot

Fibrinogen

How Axiostat Effectively Stops Bleeding in Emergencies & Trauma

Charge based adhesion between the blood components and Axiostat.
Resting Platelets
Activated Platelets
Platelet Activation via Toll-like receptors (TLR)

Prothrombin

Factor X Activation

Thrombin

Clotting Cascade activation
Fibrinogen
Fibrin Clot
Fibrin Microthrombi (Plug) Formation at the bleeding site

Hemostasis Mechanism of Axiostat

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(+91) 88607 86067

Axio Biosolutions Private Limited, Ahmedabad, Gujarat, India