Minici, R., Serra, R., Maglia, C., Guzzardi, G., Spinetta, M., Fontana, F., Venturini, M. and Laganà, D., 2023. Efficacy and Safety of Axiostat® Hemostatic Dressing in Aiding Manual Compression Closure…
Read MoreEvaluation of Chitosan-Based Axiostat as Hemostatic Dressing for Endovascular Procedures in Patients with Leriche Syndrome on Anticoagulant Therapy
Publication Details
Perri, P., Curcio, F., De Luca, M., Piro, P., Trombino, S. and Cassano, R., 2025. Evaluation of Chitosan-Based Axiostat as Hemostatic Dressing for Endovascular Procedures in Patients with Leriche Syndrome on Anticoagulant Therapy. Pharmaceuticals, 18(4), p.584.
Key Findings
Hemostatic Effectiveness and safety of Axiostat for Endovascular Procedures in Patients with Leriche Syndrome on anticoagulant therapy.
Core Results
Mean Time for Hemostasis: 5.75 minutes across all patient groups.
Primary Success Rate for hemostasis:
- 100% in single and dual antiplatelet therapy groups
- 98% in anticoagulant group
- 95.5% in combined antiplatelet + anticoagulant group
Key Insights & Discussion
- Axiostat® was found to be a safe and effective hemostatic dressing for vascular access closure in endovascular procedures , even in patients on anticoagulant therapy.
- Hemostasis was achieved rapidly with Axiostat and also reducing the risk of bleeding complications.
- No adverse events were reported, and all patients recovered without further intervention.
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