Axiostat Trauma

Evaluation of Hemostatic Effectiveness in a Standard Swine Hemorrhage Model of Severe Bleeding: A Comparative Study of Chitosan Gauze and Kaolin Gauze

Publication Details

Kumar A, Agrawal A, Bharani KK, Mavely L. Evaluation of Hemostatic Effectiveness in a Standard Swine Hemorrhage Model of Severe Bleeding: A Comparative Study of Chitosan Gauze and Kaolin Gauze. International Journal of Health Technology and Innovation. 2024 Aug 20;3(02):38-47.

Key Findings

  1. Superior hemostasis effectiveness of Axiostat gauze, with a comparison to kaolin gauze
  2. Broad Spectrum Antimicrobial property of Axiostat gauze
  3. Safety profile evaluation of Axiostat gauze with particulate Release Test

Core Results

Rate of Successful Hemostasis

  • 91.7% Clinical success (no bleeding-related vascular access site complication) – 94.2%  

Mean time-to-achieving hemostasis

  • 8.9 ± 3.9 minutes. Time-to-ambulation – 462 ± 199 minutes. (around 7 and half hours) No event of thrombosis, neuropathy, AV fistula formation. No event of re bleeding complication and infection at the bleeding wound site.